Journal of Biological Chemistry: Cordycepin Continues to be an interesting Lead Compound for Cancer Therapy

Cordyceps miltaris and has been proposed as the active component of traditional medication that is reputed to alleviate a large variety of ailments (1,,3). It has been reported to have numerous biological activities, including the inhibition of cell proliferation (4,,6), induction of apoptosis (7,,10), inhibition of platelet aggregation (11), inhibition of cell migration and invasiveness (412), and inhibition of inflammation (13). In mice, cordycepin can reduce tumor formation in a model of metastasis (12) and has therefore been proposed as a cancer drug.

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